Trauma patients bleed whole blood. However, over the last three decades, trauma patients requiring resuscitation have typically received crystalloids during prehospital resuscitation and blood component therapy during in-hospital trauma resuscitation. Blood-based resuscitation, specifically the use of low titer O-positive whole blood (LTOWB), is available to very few prehospital providers. This presentation reviews a large-scale, multi-disciplinary, multi-institutional regional trauma system prehospital LTOWB program in Southwest Texas. A large urban fire-based EMS system and 18 rural EMS systems and air medical providers deployed LTOWB for the treatment of patients in hemorrhagic shock. Attendees will learn about this successful deployment of LTOWB in the prehospital setting.

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